What is nicotine?
A Natural Substance
Nicotine is a natural substance known as an alkaloid (a chemical compound containing nitrogen atoms). “Alkaloid” derives from the word “alkaline,” which describes any nitrogen-containing base. Alkaloids are produced by plants, animals and other organisms.
When nicotine enters the body, it is distributed through the blood. It takes about seven seconds for it to reach the brain when inhaled, and it’s half-life in the body is about two hours.
Nicotine increases the levels of several neurotransmitters. The increased levels of dopamine in the reward circuits of the brain causes pleasure, relaxation and addiction.
Nicotine has many of the same qualities of caffeine. Although it can be addictive and a stimulant, it has not been proven to be a cause of cancer.
Nicotine’s effects on your mood
The way nicotine affects one’s mood differs from person to person. Since it causes a release of glucose from the liver and adrenaline from the adrenal medulla, nicotine use results in stimulation. Smokers experience relaxation, sharpness, calmness and alertness. By reducing the appetite and raising the metabolism, many smokers lose weight. Research suggests that when smokers want a stimulating effect, they take short, quick puffs. This produces a low level of blood nicotine and stimulates nerve transmission. When they want a relaxing effect, they take deep puffs. This produces a high level of blood nicotine, which depresses the passage of nerve impulses and produces a mild sedative effect.
Nicotine is unique because its profile changes from stimulant to sedative/pain killer in increasing dosages and use. At low doses, nicotine enhances the actions of norepinephrine and dopamine in the brain, causing a stimulant effect. At higher doses, nicotine enhances the effect of serotonin and opiate activity, producing a calming, pain-killing effect.
Addiction
Nicotine produces a number of effects in the brain. It activates reward pathways, which are the circuitry within the brain that regulates feelings of pleasure and euphoria. Dopamine is one of the key neurotransmitters in the brain. Since nicotine increases the levels of dopamine within the reward circuits of the brain, it has intense addictive qualities.
Therapeutic use
The primary therapeutic use of nicotine is in treating nicotine dependence to eliminate tobacco smoking. Controlled levels of nicotine are given to patients through chewing gum, patches, lozenges, electronic cigarettes or nasal sprays.
Nicotine itself, however, has also been shown to be of therapeutic value to patients. For example, a large body of evidence suggests that the risks of Parkinson’s disease or Alzheimer’s disease might be twice as high for non-smokers than for smokers.
Recent studies have also indicated that nicotine can be used to help adults suffering from autosomal dominant nocturnal frontal lobe epilepsy. The same areas that cause seizures in that form of epilepsy are also responsible for processing nicotine in the brain.
All of these studies are based only on observation, and no interventional (randomized) studies have been done. Researchers have discovered that nicotine therapy has a positive and profound effect on the symptoms of ulcerative colitis, known as Crohn’s Disease. Research on nicotine as administered through a patch or gum is ongoing.
From White Cloud Website
Read More: http://www.whitecloudelectroniccigarettes.com/idevaffiliate/idevaffiliate.php?id=477
How it Works
- Casing
- Rigid metal design—houses and protects all functional components of the cartridge.
- Anode Collar
- Aluminum design—provides secure attachment point to the battery and carries polarized electrical current to the heating coil.
- Cathode Spindle
- Aluminum design—serves a dual purpose role as both circuit cathode and ambient air portal to vapor stack.
- Spindle Grommet
- Silicone design—provides electrical insulation between the cathode and the anode.
- Vapor Stack (3rd generation, no longer a one-piece metal tube that conducts heat)
- Bell Trap
- Food-grade silicone design that provides a rigid base for the Coil Shield while preventing fluid migration.
- Coil Shield
- Braided fiberglass sleeve heat treated to remove trace starches and oils. This process stiffens the sleeve and provides a taste neutral vapor stack. This proprietary design minimizes heat conduction to the outer casing altogether eliminating the possibility of burned lips.
- Heater coil (5 windings)
- Nothing fancy here, just 5 solid windings of ultra-fine Tungsten strand to provide a perfect balance of cartridge longevity and vapor plume.
- Scavenging Whiskers
- 3 extra long braided whiskers increase the amount of liquid contacting the heater coil, creating more vapor per puff and minimizing the risk of fouling of the cartridge.
- High density captive wadding (HDCW)
- This material has a higher liquid retention ratio, which prevents flooding of the heater coil and provides adequate liquid to be scavenged by the whiskers. This eliminates the “crackling” noise that is found in low quality cartridges. Due to its high density, use of this material exclusively would restrict airflow and make puffing difficult, so it is used only as a barrier between the coil shield and LDCW.
- Low density captive wadding (LDCW)
- This material holds a majority of the liquid captive, preventing coil flood and maintaining optimal saturation of the high density wadding. It’s secondary function is to prevent liquid from seeping over the bell trap when the cartridge is inverted.
Features & benefits of construction
- After nearly 4 generations of Simple Smoke cartridge designs, the newest version—aptly named “Smooth Draw”—provides the latest in 1-piece cartridge architecture.
- Although better than tobacco cigarettes in every way, previous electronic cigarette cartridge designs left a lot to be desired. From constant crackling and burned lips, to dry-spotting and premature burn-out; these obsolete items have paved the way for simpler and more user friendly designs.
- Lower temperature operation
- Cartridge casing never gets higher than luke warm to the touch, even on sensitive lips.
- More flavor stability means even heavy smokers won’t ruin the delicious flavoring.
- Higher resistance to fouling caused by overuse or “hot boxing”.
- Higher puff count
- Most users report over 400 puffs per cartridge with some averaging more than 450!
- Our proprietary blend of Captive Wadding holds more liquid than ever before while maintaining our signature no-leak threshold.
- More liquid means fewer cartridges, and that means you keep more money in your pocket.
- Simple Design Simply Better
- We believe that unitary design is better. By creating a one-piece cartridge with the vaporizer built in, we have eliminated virtually all the unfavorable traits found in two-piece cartridge designs.
- Our praiseworthy VIC (vaporizer in cartridge) design sets a new standard in smoking simplicity. No cleaning, no maintenance, no costly atomizer replacement. Never before has “smoking” been so easy. You don’t even need a lighter.
- When the liquid in the cartridge has been exhausted (400-450 puffs) simply throw the spent cartridge away and attach a fresh one.
- No leaking no mess
- Our cartridges are manufactured to exact tolerances and inspected by hand ensuring that every Smooth Draw cartridge meets our strict no-leak threshold.
- By their nature and design two-piece cartridges are inherently messy and prone to leaking. Additionally, their fragile external atomizer has a short life expectancy, which requires frequent and costly replacement.
|
PDF 
